CBD Oil: The Complete Guide – What Is CBD, How It Works, and How to Choose
Everything about CBD oil – from the endocannabinoid system to proper dosing. Differences between full spectrum and isolate, legal status in Croatia.
Cannabidiol (CBD) is one of over 100 cannabinoids present in the Cannabis sativa plant. Unlike THC, CBD does not cause psychoactive effects ("high") but shows a range of therapeutic properties confirmed by clinical research.
How Does CBD Work in the Body?
Our body has an endocannabinoid system (ECS) that regulates numerous physiological processes including pain, mood, sleep, appetite, and immunity. The ECS consists of endocannabinoids, receptors (CB1 and CB2), and enzymes.
CBD doesn't bind directly to CB1 and CB2 receptors but acts indirectly – modulating their activity and influencing levels of endogenous cannabinoids like anandamide. It also activates serotonin (5-HT1A), vanilloid (TRPV1), and GPR55 receptors.
Scientifically Proven Benefits of CBD
Area
Evidence
Research
Anxiety
Reduces social anxiety
Bergamaschi et al., 2011
Pain
Anti-inflammatory and analgesic effects
Hammell et al., 2016
Sleep
Improves sleep quality and duration
Shannon et al., 2019
Epilepsy
FDA-approved medication (Epidiolex)
Devinsky et al., 2017
Inflammation
Reduces chronic inflammation
Burstein, 2015
Types of CBD Products
Type
Contains
Advantages
Disadvantages
Full Spectrum
CBD + THC (<0.2%) + other cannabinoids + terpenes
Entourage effect, most effective
May contain traces of THC
Broad Spectrum
CBD + other cannabinoids + terpenes, WITHOUT THC
Entourage effect without THC
Slightly less effective than full spectrum
CBD Isolate
Only pure CBD (99%+)
No THC, no smell/taste
No entourage effect
What Is the Entourage Effect? When all cannabinoids, terpenes, and flavonoids are used together, they enhance each other's effects. Full spectrum CBD is therefore more effective than pure CBD isolate.
●Type – Full spectrum for maximum effectiveness, isolate to avoid THC
●Hemp source – Organic farming, pesticide-free, European hemp
●Lab tests – COA (Certificate of Analysis) from an independent laboratory
●Extraction method – CO2 extraction is the purest and safest
●Carrier oil – MCT coconut oil for the best bioavailability
Proper CBD Dosing
There is no universal CBD dose as it depends on body weight, metabolism, desired effect, and individual sensitivity. The "Start Low, Go Slow" principle is recommended.
Body Weight
Mild Effect
Moderate Effect
Strong Effect
50–70 kg
10–15 mg
15–25 mg
25–40 mg
70–90 kg
15–20 mg
25–35 mg
35–50 mg
90+ kg
20–30 mg
30–45 mg
45–60 mg
Sublingual application (drops under the tongue) gives the fastest results – effects onset in 15–30 minutes. Hold the oil under your tongue for 60–90 seconds before swallowing.
CBD Legal Status in Croatia
In Croatia, CBD is legal if the product contains less than 0.2% THC. CBD oils are sold as dietary supplements. All Faga.bio CBD products fully comply with Croatian and EU regulations.
Our CBD Product Range
Faga.bio offers premium CBD oil with 6% CBD and 4% CBG. Our oil is full spectrum, organic, and lab-tested. Available in 10ml and 20ml packages.
FAQ
Sources / Izvori
Abu-Hashem S, Al-Dahhan A, Alshammari A, Brierley D, Taylor L, O'Sullivan SE, Karsan N (2024). Pharmacokinetics of Cannabidiol: A Systematic Review and Meta-Regression Analysis. Cannabis Cannabinoid Res. PMID: 37643301
Yoon HY, Kim J, Choi C, Choi YK, Jeong SH (2024). Quantitative summary on the human pharmacokinetic properties of cannabidiol to accelerate scientific clinical application of cannabis. Arch Pharm Res. PMID: 38850302
He W, Lu X, Wen W (2024). Therapeutic potential of cannabidiol (CBD) in anxiety disorders: A systematic review and meta-analysis. Psychiatry Res. PMID: 38924898
Taghour MS, Carandang RR, Salgado-Kent L, Puzantian T (2023). Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic Review. Pain Manag Nurs. PMID: 37953193
Gorges M, Hiemke C, Schoretsanitis G (2022). Cannabidiol in clinical and preclinical anxiety research. A systematic review into concentration-effect relations using the IB-de-risk tool. Br J Clin Pharmacol. PMID: 35133642
Millar SA, Stone NL, Bellman ZD, Yates AS, Maccabe JH, Thornton CM, O'Sullivan SE (2019). A systematic review of cannabidiol dosing in clinical populations. Br J Clin Pharmacol. PMID: 31526715
